Fiber triggers molecular mechanisms to protect the body against influenza

21.01.2025/00/30 XNUMX:XNUMX    331

Strengthening the immune system is possible not only through vaccination, but also through natural methods, such as consuming fiber, which promotes the formation of short-chain fatty acids (SCFA) in the intestines, which positively affect the immune response and reduce the risk of complications from viral infections.

by @freepik

SCFAs are produced by intestinal microflora during the digestion of dietary fiber. They strengthen the protective properties of respiratory tract cells, reduce the number of pathogens and increase the effectiveness of vaccines. Studies confirm that flu patients often have a deficiency of the bacteria that produce these beneficial acids, which emphasizes the importance of a healthy intestinal microflora for immunity.

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The Chinese University of Hong Kong has developed an innovative synbiotic, SIM01, that stimulates the growth of SCFA-producing bacteria. In a large-scale study published in The Lancet Infectious Diseases, SIM01 was found to significantly increase SCFA concentrations in patients who had recovered from COVID-19, suggesting its potential as an additional means of boosting immunity.

The effectiveness of natural SCFAs produced by the gut microbiota is superior to their synthetic counterparts. However, the prospects for artificially created SCFAs remain unexplored. Such data highlight the importance of a comprehensive approach to maintaining health, where a diet with sufficient fiber becomes a key element in the fight against viruses, including influenza and COVID-19.

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